Human gut study questions probiotic health benefits

Probiotics are found in everything from chocolate and pickles to hand lotion and baby formula, and millions of people buy probiotic supplements to boost digestive health. But new research suggests they might not be as effective as we think. Through a series of experiments looking inside the human gut, researchers show that many people's digestive tracts prevent standard probiotics from successfully colonizing them. Furthermore, taking probiotics to counterbalance antibiotics could delay the return of normal gut bacteria and gut gene expression to their naïve state. The research publishes as two back-to-back papers on September 6 in the journal Cell.  
Posted: 2018-09-11

Optimizing technologies for discovering cancer cell mutations

After three decades of hopes tempered by setbacks, gene therapy -- the process of treating a disease by modifying a person's DNA -- is no longer the future of medicine, but is part of the present-day clinical treatment toolkit. The Jan. 12 issue of the journal Science provides an in-depth and timely review of the key developments that have led to several successful gene therapy treatments for patients with serious medical conditions.  
Posted: 2018-09-11

DNA accessibility, gene expression jointly profiled in thousands of cells


Scientists have now developed an assay that concurrently profiles both the epigenome and transcriptome of each of thousands of single cells.

The epigenome and transcriptome are part of the molecular biology that converts a genetic blueprint into tools and materials for living cells.

Posted: 2018-09-11
1 - 3 of 3 Items