Gene Science and Engineering

ISSN: 2529-7651 (Online)

Journal Abbreviation: Gene Sci Eng

Publication Frequency: irregular

Article Processing Charges (APC): Click here for more details

Publishing Model: Open Access

Journal no: 17P

About the Journal

The aim of Gene Science and Engineering is to publish substantial and novel findings regarding all aspects related to gene science and genetic engineering, research work and applications using recombinant DNA, gene editing and related molecular genetics methods. The journal will also publish biochemical and biophysical research work on biological macromolecules and metabolic products, including biochemical profiling and other approaches to functional genomics and metabolic research. The journal aims to provide a rapid turn-around time possible for reviewing and publishing, and to disseminate the articles for research, teaching and reference purposes.

Recently Published Articles

Original Research Articles

Zhou Zongwei
8 Views, 10 PDF Downloads

Pine is a relatively easy genus for intermediate hybridization. It has been widely believed that there should be a
natural hybrid population in the distribution of Pinus massoniona Lamb. and Pinus hangshuanensis Hsia, that is, the
excessive type of external form between Pinus massoniana and Pinus taiwanensis exist. This paper mainly discusses
the traits and clustering analysis of coniferous lozeng in Huangshan scenic area. This study will provide a theoretical
basis for the classification of long and outstanding Huangshan Song and so on. At the same time, it will provide
reference for the phenomenon of gene seepage between the two species.


Original Research Articles

Ceng Yiwu
8 Views, 10 PDF Downloads

Differentiated somatic cells can be reprogrammed into induced pluripotent stem cells (iPS cells) by introducing
specific transcription factors. This technique avoids immune rejection and ethical problems in stem cell research.
A great revolution in the fi eld of science. As with embryonic stem cells (ES cells), iPS cells are able to self-renew
and maintain undiff erentiated state. In vitro, iPS cells can be induced to diff erentiate into a variety of mature cells,
therefore, iPS cells in theoretical research and clinical applications are extremely valuable. IPS cell diff erentiation
and transplantation in the treatment of blood diseases have a great use, iPS cells can treat nervous system diseases,
to provide in vitro disease model, to study the mechanism of disease formation, screening new drugs and the
development of new to provide a new treatment The The use of iPS cells as a nuclear donor cell, with the appropriate
receptor cells after fusion can be directly obtained transgenic animals. Not only can improve the genetic nature of
animals, but also can break the boundaries of species and get the new animal traits that cannot achieve by using
traditional mating methods. The research of iPS cells has been widely concerned, and it is the research hotspot in cell
biology and molecular biology. In this paper, the defi nition of iPS cells, the acquisition of iPS cells, the history of
development, the signifi cance of research, the progress of research, the application of iPS cells, and the problems of
iPS cells were reviewed.


Original Research Articles

Gao Chengcheng
8 Views, 29 PDF Downloads

γ-amino butyric acid (GABA) is a non-protein amino acid widely distributed in nature. It has analgesic effect,
promotes growth hormone secretion and prevents the physiological function of Alzheimer's disease.In order to
improve the yield of GABA, the strain of strain HX-3-6 was tested by Atmospheric and Room Temperature Plasma
(ARTP), and the strain with more than 90% lethality was selected for fermentation, and through the gradient plate
according to the level of GABA concentration and colony size of the screening. Then, use the fermentation medium
for re-screening and genetic stability test. The yield of the mutant strain L-120-1 was 5.828 g/L, which was 18.84%
higher than that before the mutation (4.904). The mutant strain L-120-1 was used as the starting strain for ARTP
mutagenesis. The yield of the stable mutant strain 90s-high was 6.178g / L, which was 16.15% higher than that before
the mutation (5.319g / L). The yield of HX-3-6 strain was higher than that of GABA mutant strain 90s-high 2, which
was stable and high yield GABA was 25.98%.


Original Research Articles

Liu Feifei
15 Views, 11 PDF Downloads

Foot-and-mouth disease is an acute and highly contagious viral infectious disease. Although the foot and mouth
disease vaccine has been applied in some parts of the world since the beginning of the 20th century, the current
epidemic of foot and mouth disease in the world is still serious and constitutes an obstacle to the trade of animal and
animal products in the world. The porcine pseudorabies virus gene deletion strain PRV TK-/ gE-/ LacZ +, which is
constructed by our laboratory, has the advantages of good safety, large capacity and high recombination effi ciency. In
this study, the artifi cial O-type foot-and-mouth disease P1 gene as an antigen gene, UbiP1 fused with ubiquitin (Ub)
as another antigen gene to enhance cellular immunity, and then shRNA designed for FMD 3B gene and porcine IFN-
[gamma] with antiviral and immune-regulatory eff ects. The two functional genes were constructed in turn to construct
a transfer vector with four functional genes. The transfer vector was transfected into TK-/ gE- / LacZ+ cells with PRV
deletion vector, and the plasmids were purifi ed and identifi ed. The recombinant pseudorabies virus, which contains
the six functional genes of P1 gene, UbiP1, shRNA and IFN-γ, was obtained, which laid the foundation for further
construction of new genetically engineered vaccine.


Original Research Articles

Ku Weihao
14 Views, 10 PDF Downloads

Micronucleus is an abnormal structure in eukaryotic cells. It is the result of various physical and chemical factors,
such as radiation and chemical drugs acting on dividing cells. It is generally believed that micronuclei are originated
in backward chromosomes and fragments that have lost centromere and are formed at the end of mitosis. However,
other experiments suggest that interphase cells can also form micronuclei. In this study, human peripheral blood
lymphocytes were cultured in vitro and cyclophosphamide 20 ug/ml was injected at specifi c times of the cell cycle to
observe the relationship between micronuclei formation and cell cycle. The experimental results confi rmed that the
cell cycle micronucleus formation.

Read more

Indexing and Archiving

Gene Science and Engineering(GSE) aims to be indexed by world-recognized databases, for example, PubMed, Scopus and Science Citation Index (SCI). GSE has been indexed and archived by several databases:

Editorial Board

Coming Soon!

Focus and Scope

The aim of Gene Science and Engineering is to publish substantial and novel findings regarding all aspects related to gene science and genetic engineering, research work and applications using recombinant DNA, gene editing and related molecular genetics methods. The journal will also publish biochemical and biophysical research work on biological macromolecules and metabolic products, including biochemical profiling and other approaches to functional genomics and metabolic research. The journal aims to provide a rapid turn-around time possible for reviewing and publishing, and to disseminate the articles for research, teaching and reference purposes.

Publishing original research articles and reviews, Gene Science and Engineering reports on significant new contributions to the field, combining curiosity-driven studies with the potential for application.

Principal areas covered in Gene Science and Engineering include:

  1. Research work and applications using recombinant DNA, gene editing and related molecular genetics methods.
  2. Biochemical, biophysical and structural research work on biological macromolecules and metabolic products, including biochemical profiling and other approaches to functional genomics and metabolic research.
  3. Research work within the wider scope of biotechnology, covering applications to biomedicine, genetic modification of animals, plants and microorganisms.
  4. Applied research for the development of environmental and industrial biotechnological products and processes.
  5. Report of new methods in genetic engineering.

For Authors

  • A manuscript would not be accepted if it has been published or is currently under consideration for publication in any other journals. The author will need to notify the editorial team if the data in their submission has been presented in conferences.

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Article Processing Charges (APC)

Gene Science and Engineering is an Open Access Journal under Whioce Publishing. All articles published in Gene Science and Engineering are accessible electronically from the journal website without commencing any kind of payment. In order to ensure contents are freely available and maintain publishing quality, Article Process Charges (APC) is applicable to all authors who wish to submit their articles to the journal to cover the cost incurred in processing the manuscripts. Such cost will cover the peer-review, copyediting, typesetting, publishing, content depositing and archiving processes. Those charges are applicable only to authors who have their manuscript successfully accepted after peer-review.

Journal TitleAPC
Gene Science and Engineering$800

We encourage authors to publish their papers with us and don’t wish the cost of article processing fees to be a barrier especially to authors from the low and lower middle income countries/regions. A range of discounts or waivers are offered to authors who are unable to pay our publication processing fees. Authors can write in to apply for a waiver and requests will be considered on a case-by-case basis.

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Frequently Asked Questions

  • Answer: To establish whether your paper is suitable for this journal, please read Focus and Scope under Editorial Policies.
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Whioce Publishing Pte Ltd  and the Editor-in-chief invite all authors  to submit their  manuscripts to  our  newly launched  journal, Gene Science and Engineering, for peer review.

Posted: 2017-06-08
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