Gene Science and Engineering

ISSN: 2529-7651 (Online)

Journal Abbreviation: Gene Sci Eng

Publication Frequency: irregular

Article Processing Charges (APC): Click here for more details

Publishing Model: Open Access

Journal no: 17P

About the Journal

The aim of Gene Science and Engineering is to publish substantial and novel findings regarding all aspects related to gene science and genetic engineering, research work and applications using recombinant DNA, gene editing and related molecular genetics methods. The journal will also publish biochemical and biophysical research work on biological macromolecules and metabolic products, including biochemical profiling and other approaches to functional genomics and metabolic research. The journal aims to provide a rapid turn-around time possible for reviewing and publishing, and to disseminate the articles for research, teaching and reference purposes.

Recently Published Articles

Original Research Articles

Zhou Zongwei
8 Views, 10 PDF Downloads

Pine is a relatively easy genus for intermediate hybridization. It has been widely believed that there should be a
natural hybrid population in the distribution of Pinus massoniona Lamb. and Pinus hangshuanensis Hsia, that is, the
excessive type of external form between Pinus massoniana and Pinus taiwanensis exist. This paper mainly discusses
the traits and clustering analysis of coniferous lozeng in Huangshan scenic area. This study will provide a theoretical
basis for the classification of long and outstanding Huangshan Song and so on. At the same time, it will provide
reference for the phenomenon of gene seepage between the two species.

PDF

Original Research Articles

Ceng Yiwu
8 Views, 10 PDF Downloads

Differentiated somatic cells can be reprogrammed into induced pluripotent stem cells (iPS cells) by introducing
specific transcription factors. This technique avoids immune rejection and ethical problems in stem cell research.
A great revolution in the fi eld of science. As with embryonic stem cells (ES cells), iPS cells are able to self-renew
and maintain undiff erentiated state. In vitro, iPS cells can be induced to diff erentiate into a variety of mature cells,
therefore, iPS cells in theoretical research and clinical applications are extremely valuable. IPS cell diff erentiation
and transplantation in the treatment of blood diseases have a great use, iPS cells can treat nervous system diseases,
to provide in vitro disease model, to study the mechanism of disease formation, screening new drugs and the
development of new to provide a new treatment The The use of iPS cells as a nuclear donor cell, with the appropriate
receptor cells after fusion can be directly obtained transgenic animals. Not only can improve the genetic nature of
animals, but also can break the boundaries of species and get the new animal traits that cannot achieve by using
traditional mating methods. The research of iPS cells has been widely concerned, and it is the research hotspot in cell
biology and molecular biology. In this paper, the defi nition of iPS cells, the acquisition of iPS cells, the history of
development, the signifi cance of research, the progress of research, the application of iPS cells, and the problems of
iPS cells were reviewed.

PDF

Original Research Articles

Gao Chengcheng
8 Views, 29 PDF Downloads

γ-amino butyric acid (GABA) is a non-protein amino acid widely distributed in nature. It has analgesic effect,
promotes growth hormone secretion and prevents the physiological function of Alzheimer's disease.In order to
improve the yield of GABA, the strain of strain HX-3-6 was tested by Atmospheric and Room Temperature Plasma
(ARTP), and the strain with more than 90% lethality was selected for fermentation, and through the gradient plate
according to the level of GABA concentration and colony size of the screening. Then, use the fermentation medium
for re-screening and genetic stability test. The yield of the mutant strain L-120-1 was 5.828 g/L, which was 18.84%
higher than that before the mutation (4.904). The mutant strain L-120-1 was used as the starting strain for ARTP
mutagenesis. The yield of the stable mutant strain 90s-high was 6.178g / L, which was 16.15% higher than that before
the mutation (5.319g / L). The yield of HX-3-6 strain was higher than that of GABA mutant strain 90s-high 2, which
was stable and high yield GABA was 25.98%.

PDF

Original Research Articles

Liu Feifei
15 Views, 11 PDF Downloads

Foot-and-mouth disease is an acute and highly contagious viral infectious disease. Although the foot and mouth
disease vaccine has been applied in some parts of the world since the beginning of the 20th century, the current
epidemic of foot and mouth disease in the world is still serious and constitutes an obstacle to the trade of animal and
animal products in the world. The porcine pseudorabies virus gene deletion strain PRV TK-/ gE-/ LacZ +, which is
constructed by our laboratory, has the advantages of good safety, large capacity and high recombination effi ciency. In
this study, the artifi cial O-type foot-and-mouth disease P1 gene as an antigen gene, UbiP1 fused with ubiquitin (Ub)
as another antigen gene to enhance cellular immunity, and then shRNA designed for FMD 3B gene and porcine IFN-
[gamma] with antiviral and immune-regulatory eff ects. The two functional genes were constructed in turn to construct
a transfer vector with four functional genes. The transfer vector was transfected into TK-/ gE- / LacZ+ cells with PRV
deletion vector, and the plasmids were purifi ed and identifi ed. The recombinant pseudorabies virus, which contains
the six functional genes of P1 gene, UbiP1, shRNA and IFN-γ, was obtained, which laid the foundation for further
construction of new genetically engineered vaccine.

PDF

Original Research Articles

Ku Weihao
14 Views, 10 PDF Downloads

Micronucleus is an abnormal structure in eukaryotic cells. It is the result of various physical and chemical factors,
such as radiation and chemical drugs acting on dividing cells. It is generally believed that micronuclei are originated
in backward chromosomes and fragments that have lost centromere and are formed at the end of mitosis. However,
other experiments suggest that interphase cells can also form micronuclei. In this study, human peripheral blood
lymphocytes were cultured in vitro and cyclophosphamide 20 ug/ml was injected at specifi c times of the cell cycle to
observe the relationship between micronuclei formation and cell cycle. The experimental results confi rmed that the
cell cycle micronucleus formation.

PDF
Read more

Indexing and Archiving

Gene Science and Engineering(GSE) aims to be indexed by world-recognized databases, for example, PubMed, Scopus and Science Citation Index (SCI). GSE has been indexed and archived by several databases:

Editorial Board

Coming Soon!

Focus and Scope

The aim of Gene Science and Engineering is to publish substantial and novel findings regarding all aspects related to gene science and genetic engineering, research work and applications using recombinant DNA, gene editing and related molecular genetics methods. The journal will also publish biochemical and biophysical research work on biological macromolecules and metabolic products, including biochemical profiling and other approaches to functional genomics and metabolic research. The journal aims to provide a rapid turn-around time possible for reviewing and publishing, and to disseminate the articles for research, teaching and reference purposes.

Publishing original research articles and reviews, Gene Science and Engineering reports on significant new contributions to the field, combining curiosity-driven studies with the potential for application.

Principal areas covered in Gene Science and Engineering include:

  1. Research work and applications using recombinant DNA, gene editing and related molecular genetics methods.
  2. Biochemical, biophysical and structural research work on biological macromolecules and metabolic products, including biochemical profiling and other approaches to functional genomics and metabolic research.
  3. Research work within the wider scope of biotechnology, covering applications to biomedicine, genetic modification of animals, plants and microorganisms.
  4. Applied research for the development of environmental and industrial biotechnological products and processes.
  5. Report of new methods in genetic engineering.

For Authors

  • A manuscript would not be accepted if it has been published or is currently under consideration for publication in any other journals. The author will need to notify the editorial team if the data in their submission has been presented in conferences.

  • Authorship should be limited to people who have contributed substantially to the work. Authors must indicate their specific contributions to the published work. This information should be listed in the manuscript under the section ‘Author Contribution’. Examples of contributions include: designed research, performed research, contributed new reagents or analytic tools, analyzed data, wrote the paper.

    For more information on submission’s format, please refer to the ‘Author Guidelines’ link accessible from the ‘About’ button at the top row of this page.

    The corresponding author should be clearly indicated for all manuscripts submitted. A maximum of two corresponding authors are allowed for the responsibilities associated. The corresponding author(s) is responsible for:

    • Obtaining permission from all the authors mentioned in the manuscript
    • Ensuring adherence to all editorial and submission policies and for any communications and actions that may be necessary after publication
    • Including written permission from the authors of the work concerned for any mention of any unpublished material included in the manuscript, e.g. data from manuscripts-in-press, personal communication, or work in preparation.
  • The author has to provide the authorization of no conflict with any financial body or funding agency that might influence the results or interpretation of their manuscript. All authors, members, reviewers and editors must disclose any association that poses a conflict of interest in connection with the manuscript. The corresponding author will be asked to sign a form behalf of all of the authors regarding potential conflicts of interest at the time of acceptance.

  • The editorial team does not approve of any plagiarism attempts. iThenticate will be utilized at the editor’s discretion to verify the originality of submitted manuscripts. If plagiarism is detected during the review process the manuscript may be rejected pending the severity of plagiarism. Therefore, if a manuscript uses a text copied directly from another source, this text must be written in quotation marks and the original source must be cited.

  • All articles must be written in English — preferably American English. SI units should be used. If you are not a native English speaker, you may want to utilize an external or Whioce Publishing’s optional professional language editing service before submitting the final version.

  • Whioce Publishing Pte Ltd offers its own professional editing services. By using this service, you can be sure that your English-language manuscript will be polished and ready for submission to your publication of choice at a very reasonable price. For further details about the Language Editing Services, please contact us at editorial@whioce.com. Please note that utilizing a language editing service is not a guarantee of acceptance.

  • Revised manuscripts must contain a detailed point by point response to the comments of the reviewers. The response to reviewers has to be uploaded as a separate file.

  • If you withdraw your manuscript after it has been accepted (but not yet published), you will be charged for costs incurred at USD200.

  • Authors are expected to have minimum amount of post-acquisition processing of data. In case of processing; alterations must be applied to the entire image (e.g., brightness, contrast, color balance). Any kind of alteration if being done has to be clearly stated in the figure legend and in Methods section.

    Grouping of data (e.g., cropping of images of removal of lanes from gels and bolts) must be made apparent and should be explicitly indicated in the appropriate figure legends. Data comparisons should only be made from comparative experiments, and individual data should not be utilized across multiple figures. If inappropriate image/data manipulation is identified after publication, we reserve the right to ask for the original data and, if that is not satisfactory, to issue a correction or retract the paper, as appropriate.

  • Whioce Publishing will preserve e-journals with Portico, ensuring that they will be secure and available into the future.

  • Authors contributing to Whioce Publishing Pte. Ltd. agree to publish their articles under the Creative Commons Attribution-Noncommercial 4.0 International License, allowing third parties to share their work (copy, distribute, transmit) and to adapt it, under the condition that the authors are given credit, that the work is not used for commercial purposes, and that in the event of reuse or distribution, the terms of this license are made clear.
  • The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.

Article Processing Charges (APC)

Gene Science and Engineering is an Open Access Journal under Whioce Publishing. All articles published in Gene Science and Engineering are accessible electronically from the journal website without commencing any kind of payment. In order to ensure contents are freely available and maintain publishing quality, Article Process Charges (APC) is applicable to all authors who wish to submit their articles to the journal to cover the cost incurred in processing the manuscripts. Such cost will cover the peer-review, copyediting, typesetting, publishing, content depositing and archiving processes. Those charges are applicable only to authors who have their manuscript successfully accepted after peer-review.

Journal TitleAPC
Gene Science and Engineering$800

We encourage authors to publish their papers with us and don’t wish the cost of article processing fees to be a barrier especially to authors from the low and lower middle income countries/regions. A range of discounts or waivers are offered to authors who are unable to pay our publication processing fees. Authors can write in to apply for a waiver and requests will be considered on a case-by-case basis.

Authors based in these countries/regions listed below may apply to receive up to a 50%-100% waiver of the standard article processing fee; Waiver subjected to approval.

  • Afghanistan
  • Armenia
  • Bangladesh
  • Benin
  • Bhutan
  • Bolivia
  • Burkina Faso
  • Burundi
  • Cabo Verde
  • Cambodia
  • Cameroon
  • Central African Republic
  • Chad
  • Comoros
  • Congo, Dem. Rep
  • Congo, Rep.
  • Côte d'Ivoire
  • Djibouti
  • Egypt, Arab Rep.
  • El Salvador
  • Eritrea
  • Ethiopia
  • Gambia, The
  • Ghana
  • Guatemala
  • Guinea
  • Guinea-Bissau
  • Haiti
  • Honduras
  • India
  • Indonesia
  • Kenya
  • Kiribati
  • Korea, Dem. People's Rep.
  • Kosovo
  • Kyrgyz Republic
  • Lao PDR
  • Lesotho
  • Liberia
  • Madagascar
  • Malawi
  • Mali
  • Mauritania
  • Micronesia, Fed. Sts.
  • Moldova
  • Mongolia
  • Morocco
  • Mozambique
  • Myanmar
  • Nepal
  • Nicaragua
  • Niger
  • Nigeria
  • Pakistan
  • Papua New Guinea
  • Philippines
  • Rwanda
  • Samoa
  • São Tomé and Principe
  • Senegal
  • Sierra Leone
  • Solomon Islands
  • Somalia
  • South Sudan
  • Sri Lanka
  • Sudan
  • Swaziland
  • Syrian Arab Republic
  • Tajikistan
  • Tanzania
  • Timor-Leste
  • Togo
  • Tonga
  • Tunisia
  • Uganda
  • Ukraine
  • Uzbekistan
  • Vanuatu
  • Vietnam
  • West Bank and Gaza
  • Yemen, Rep.
  • Zambia
  • Zimbabwe

If you are residing in one of the above mentioned countries and need to apply for a waiver, please email our editorial department (editorial@whioce.com) with the following information:

  • Your name and institution with full address details
  • Title of journal you wish to submit a manuscript to
  • Reason for applying for a waiver
  • Title of your paper
  • Country of residence of all co-author

APC Payment

Payments for APC of this journal can be made through our online PayPal payment gateway. Enter the article no. into the below textbox and select "Pay Now" to proceed with payment.

Article No.

*Article No. is mandatory for payment and it can be found on the acceptance letter issued by the Editorial Office. Payment without indicating Article No. will result in processing problem and delay in article processing. Please note that payments will be processed in USD. You can make payment through Masters, Visa or UnionPay card.

Frequently Asked Questions

  • Answer: To establish whether your paper is suitable for this journal, please read Focus and Scope under Editorial Policies.
  • Answer: Registration and login are required to submit manuscript online and to check the status of current submission.
  • Answer: The submission file can be submitted in OpenOffice, Microsoft Word, RTF, or WordPerfect document file format.
  • Answer: The length of the manuscript cannot be more than 8000 words.
  • Answer: The cover letter is necessary for each submission. The cover letter should be uploaded as a separate file in Step 4 during the submission. The contents of the cover letter should include brief explanation of what was previously known, the conceptual advancement with the findings and its significance to broad readership. The cover letter will only be visible to the editor. Reviewers will not have access to the cover letter.
  • Answer: You can suggest 2 reviewers for your submission. However, the decision of whether to invite them lies with the Editor.
  • Answer: This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Refer to the Publication Fees tab for more details.

Announcements

 

Call-for-Papers

 

Whioce Publishing Pte Ltd  and the Editor-in-chief invite all authors  to submit their  manuscripts to  our  newly launched  journal, Gene Science and Engineering, for peer review.

 
Posted: 2017-06-08
 
More Announcements...