Biomed Communication

ISSN: 2529-7635 (Online)

Journal Abbreviation: Biomed Commun

Publication Frequency: irregular

Article Processing Charges (APC): Click here for more details

Publishing Model: Open Access

About the Journal

Biomedical Communications is an international open access journal that publishes original research articles and reviews articles in all areas of biomedicine.

Vol 2, Issue 3 ( In publishing)

Table of Contents

Original Research Articles

by Guillermo Guillen-Gamez, Héctor Migallón
404 Views, 463 PDF Downloads

High-throughput biological technologies are now widely applied in biology and medicine, allowing scientists to monitor thousands of parameters simultaneously in a specific sample. However, it is still an enormous challenge to mine useful information from high-throughput data. The emergence of network biology provides deeper insights into complex bio-system and reveals the modularity in tissue/cellular networks. Correlation networks are increasingly used in bioinformatics applications. Weighted gene co-expression network analysis (WGCNA) tool can detect clusters of highly correlated genes. Therefore, we systematically reviewed the application of WGCNA in the study of disease diagnosis, pathogenesis and other related fields. First, we introduced principle, workflow, advantages and disadvantages of WGCNA. Second, we presented the application of WGCNA in disease, physiology, drug, evolution and genome annotation. Then, we indicated the application of WGCNA in newly developed high-throughput methods. We hope this review will help to promote the application of WGCNA in biomedicine research.



Call for Papers: 2019

Posted: 2019-03-27 More...
More Announcements...